Detox and binders
Does deferoxamine reduce bone aluminum in dialysis patients?
In a case series, bone aluminum was absent or reduced in 3 dialysis patients who had a repeat biopsy after deferoxamine. A later randomized comparison of two doses, without placebo, found similar response rates at the low dose and the standard dose. These studies do not establish a population benefit beyond aluminum overload in dialysis.
Studies
- Malluche 1984: uncontrolled series, 7 treated dialysis patients, repeat biopsy in 3. Bone aluminum absent or reduced in those 3. The serum-rise test was not diagnostic. PMID 6377067.
- Kan 2010: 21 versus 21 hemodialysis patients with aluminum overload. Success in 13 of 21 on the low dose and 12 of 21 on the standard dose, P=0.75. No placebo. doi:10.1093/ndt/gfp649. PMID 19948879.
Related pages
Sources
Heavy Metal Index
Heavy Metal Index: Aluminum. This Heavy Metal Index URL returned HTTP 200 on 15 October 2026. Figures on this page are not copied from that index. They come from the sources named above.
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This page summarizes cited documents. It does not diagnose or prescribe. Reviewed 15 October 2026.